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This research was carried out to evaluate the potential in the CPPs with tumor-targeting Houses to deliver a cytotoxic payload to HCC cells. We explored employing a CXCR4-concentrating on peptide, T22, fused with cytotoxic peptide PE24, being a novel therapeutic tactic for CXCR4+ HCC cells. T22 was chosen as the nanocarrier due to its effectively-r